Sinequan Drug Info
Sinequan Drug Uses: Sinequan is used to elevate the mood of patients with depression. Nortriptyline is also a sedative and is useful in depressed patients with insomnia, restlessness, and nervousness. Sinequan also has been found to be helpful for treating chronic pain and the pain of neuralgia.
How to Use Sinequan: The dose of Sinequan is tailored to the patient's needs. Sometimes, physicians will start with relatively low doses, such as 25mg, given three times a day, to reduce the risk of excessive sedation early in the course; doses then will be increased slowly. (It may take several weeks before the effects of a dose are maximal.) Other physicians prefer to give nortriptyline once daily, in which case it is generally given at bedtime to take advantage of its sedating properties. Elderly persons and patients with advanced liver disease may need lower doses.
Sinequan Precautions: Cimetidine (Tagamet) can increase doxepin blood levels, possibly causing side effects. There is very little information about the effects of Sinequan on the fetus in pregnant women. Physicians may use doxepin it if its benefits are deemed to outweigh the unknown risks.
Sinequan Drug Interactions: Sinequan exaggerates the effects of other medications and drugs that slow the brain's processes, such as alcohol, barbiturates, benzodiazepines (e.g. lorazepam, Ativan), and narcotics. Reserpine, given to patients taking TCAs, can have a stimulatory effect. Doxepin and other TCAs should not be used with monoamine oxidase inhibiting drugs, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane). High fever, convulsions and even death can occur when these drugs are used together.
Sinequan Possible Side Effects: The most commonly encountered side effects associated with doxepin include rapid heart rate, blurred vision, urinary retention (difficulty urinating), dry mouth, constipation, weight gain or loss, and low blood pressure when going from sitting to standing orthostatic hypotension). Rash, hives, seizures, and hepatitis are rare side effects. Doxepin also can cause elevated pressure in the eyes of some patients with glaucoma. Overdose with doxepin can cause life threatening abnormal heart rhythms or seizures.
Sinequan Overdose: Seek emergency medical attention immediately if an overdose is suspected. Symptoms of Sinequan overdose include: rapid heart rate, blurred vision, urinary retention (difficulty urinating), dry mouth, constipation.
Sinequan Storage: Store Sinequan at room temperature away from moisture and sunlight. Avoid excessive heat. Avoid freezing. Keep out of the reach of children. Dispense of this medicine in a tight, light-resistant container. Do not store Sinequan in the bathroom.
Sinequan Missed Dose: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Disclaimer: The information found on this website is for informational purposes only. It does not cover all possible uses, procedures, safety measures, side effects, or drug interactions of the products. We are not responsible for the accuracy and reliability of this drug information, or any consequences arising from the use of this information. This is only general information and should not be relied on for any purpose.
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